De Novo Synthesis of Multisubstituted Aryl Amines Using Alkene Cross Metathesis
نویسندگان
چکیده
The olefin cross-metathesis reaction allows rapid access to 1,5-dicarbonyl intermediates which, upon treatment with a primary or secondary amine, allow the synthesis of a range of multisubstituted carbocyclic aryl amines. This de novo arene synthesis yields nonclassical substitution patterns in a regioselective and predictable approach that is compatible with several functional groups.
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عنوان ژورنال:
دوره 16 شماره
صفحات -
تاریخ انتشار 2014